🏫 Education

2023.09–2027.06   Jiangnan University

🧭 Research Agenda

Overview of the EuclideanMamba architecture
Long-Range Atomistic Modeling

Chem-Mamba · EuclideanMamba

A linear-complexity architecture representing charge transfer, electron delocalization, and periodic response as unified source–propagation–response state dynamics.

Overview of the Verified Repair Contracts architecture
Verifiable Scientific Agents

Chem-Agent · Verified Repair Contracts

An evidence-aware control layer that verifies tool calls, performs safe repairs, and reruns all checks before scientific execution.

📄 Publications

FWMamba-UNet architecture

FWMamba-UNet: Frequency-Wavelet Enhanced Mamba UNet for Medical Image Segmentation

Zihao Guo, et al.

ICIC 2026 · Oral · First Author
AcceptedCCF-CMamba
Extract-Then-Compile framework

Extract-Then-Compile: Reliable Neuro-Symbolic Planning for Large Language Models

Zihao Guo, et al.

ICIC 2026 · Oral · First Author
AcceptedCCF-CNeuro-Symbolic AI
MambaGuard framework

MambaGuard: A CLIP-Mamba Approach for OOD Generated Image Detection

Zihao Guo*, et al.

PRCV 2025 · Co-First Author
PublishedCCF-COOD Detection
RA-Det framework

RA-Det: Towards Universal Detection of AI-Generated Images via Robustness Asymmetry

Xinchang Wang, Yunhao Chen, Yuechen Zhang, Congcong Bian, Zihao Guo, et al.

ICML 2026 · Fifth Author
AcceptedCCF-AAI-Generated Images

🧪 Research Project

AMP Forge — Antimicrobial Peptide De-Novo Design

iGEM 2025 · Gold Medal · Dry-Lab Lead

I built a protein-language-model-to-latent-diffusion workflow for antimicrobial peptide design, curated 25,622 peptides from six databases, and added an activity predictor for closed-loop screening. Multiple generated variants outperformed the original sequence in wet-lab validation.

PyTorchESM-2Latent DiffusionBiGRU-VAE

🤝 Service & Outreach

Founder and team leader of the “AI Qicheng” Coding Outreach Team. Delivered coding-literacy classes to more than 600 primary-school students in under-developed regions of Shandong. I also serve as class leader of Digital Media 2304.